Modeling Fanconi Anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs

Fanconi Anemia (FA) is a recessive disorder characterized by genomic instability, congenital abnormalities, cancer predisposition and bone marrow failure. However, the pathogenesis of FA is not fully understood partly due to the limitations of current disease models. Here, we derive integration-free...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Liu, Guang-Hui, Suzuki, Keiichiro, Li, Mo, Qu, Jing, Montserrat, Nuria, Tarantino, Carolina, Gu, Ying, Yi, Fei, Xu, Xiuling, Zhang, Weiqi, Ruiz, Sergio, Plongthongkum, Nongluk, Zhang, Kun, Masuda, Shigeo, Nivet, Emmanuel, Tsunekawa, Yuji, Soligalla, Rupa Devi, Goebl, April, Aizawa, Emi, Kim, Na Young, Kim, Jessica, Dubova, Ilir, Li, Ying, Ren, Ruotong, Benner, Chris, del Sol, Antonio, Bueren, Juan, Trujillo, Juan Pablo, Surralles, Jordi, Cappelli, Enrico, Dufour, Carlo, Esteban, Concepcion Rodriguez, Belmonte, Juan Carlos Izpisua
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291073/
https://ncbi.nlm.nih.gov/pubmed/24999918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms5330
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