Progressive degeneration of human neural stem cells caused by pathogenic LRRK2

Nuclear architecture defects have been shown to correlate with the manifestation of a number of human diseases as well as aging(1-4). It is then plausible that diseases whose manifestations correlate with aging might be connected to the appearance of nuclear aberrations over time. We decided to eval...

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Main Authors: Liu, Guang-Hui, Qu, Jing, Suzuki, Keiichiro, Nivet, Emmanuel, Li, Mo, Montserrat, Nuria, Yi, Fei, Xu, Xiuling, Ruiz, Sergio, Zhang, Weiqi, Ren, Bing, Wagner, Ulrich, Kim, Audrey, Li, Ying, Goebl, April, Kim, Jessica, Soligalla, Rupa Devi, Dubova, Ilir, Thompson, James, Yates, John, Esteban, Concepcion Rodriguez, Sancho-Martinez, Ignacio, Belmonte, Juan Carlos Izpisua
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3504651/
https://ncbi.nlm.nih.gov/pubmed/23075850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature11557
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