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Targeted Gene Correction of Laminopathy-Associated LMNA Mutations in Patient-Specific iPSCs
Combination of stem cell-based approaches with gene-editing technologies represents an attractive strategy for studying human disease and developing therapies. However, gene-editing methodologies described to date for human cells suffer from technical limitations including limited target gene size,...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3480729/ https://ncbi.nlm.nih.gov/pubmed/21596650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2011.04.019 |
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