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Genetic interaction analysis of point mutations enables interrogation of gene function at a residue-level resolution: Exploring the applications of high-resolution genetic interaction mapping of point mutations
We have achieved a residue-level resolution of genetic interaction mapping – a technique that measures how the function of one gene is affected by the alteration of a second gene – by analyzing point mutations. Here, we describe how to interpret point mutant genetic interactions, and outline key app...
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| Publicado no: | Bioessays |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4289610/ https://ncbi.nlm.nih.gov/pubmed/24842270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.201400044 |
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