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Adventures in time and space: Splicing efficiency and RNA polymerase II elongation rate
Control of pre-mRNA splicing is a critical part of the eukaryotic gene expression process. Extensive evidence indicates that transcription and splicing are spatiotemporally coordinated and that most splicing events occur co-transcriptionally. A kinetic coupling model has been proposed in metazoans t...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Landes Bioscience
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4075515/ https://ncbi.nlm.nih.gov/pubmed/24717535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/rna.28646 |
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