Pre-mRNA splicing is facilitated by an optimal RNA polymerase II elongation rate

Alternative splicing modulates expression of most human genes. The kinetic model of cotranscriptional splicing suggests that slow elongation expands and that fast elongation compresses the “window of opportunity” for recognition of upstream splice sites, thereby increasing or decreasing inclusion of...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Genes Dev
Egile Nagusiak: Fong, Nova, Kim, Hyunmin, Zhou, Yu, Ji, Xiong, Qiu, Jinsong, Saldi, Tassa, Diener, Katrina, Jones, Ken, Fu, Xiang-Dong, Bentley, David L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Cold Spring Harbor Laboratory Press 2014
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248296/
https://ncbi.nlm.nih.gov/pubmed/25452276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.252106.114
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