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Transcription elongation rate affects nascent histone pre-mRNA folding and 3′ end processing

Transcription elongation rate influences cotranscriptional pre-mRNA maturation, but how such kinetic coupling works is poorly understood. The formation of nonadenylated histone mRNA 3′ ends requires recognition of an RNA structure by stem–loop-binding protein (SLBP). We report that slow transcriptio...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Saldi, Tassa, Fong, Nova, Bentley, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5859970/
https://ncbi.nlm.nih.gov/pubmed/29483154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.310896.117
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