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Alternative RNA structures formed during transcription depend on elongation rate and modify RNA processing

Most RNA processing occurs co-transcriptionally. We interrogated nascent pol II transcripts by chemical and enzymatic probing, and determined how the “nascent RNA structureome” relates to splicing, A-I editing and transcription speed. RNA folding within introns and steep structural transitions at sp...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Saldi, Tassa, Riemondy, Kent, Erickson, Benjamin, Bentley, David
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8052309/
https://ncbi.nlm.nih.gov/pubmed/33631106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2021.01.040
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