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Quantitative Analysis of Triple Mutant Genetic Interactions

The quantitative analysis of genetic interactions between pairs of gene mutations has proven effective for characterizing cellular functions but can miss important interactions for functionally redundant genes. To address this limitation, we have developed an approach termed Triple Mutant Analysis (...

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Detalhes bibliográficos
Main Authors: Braberg, Hannes, Alexander, Richard, Shales, Michael, Xu, Jiewei, Franks-Skiba, Kathleen E., Wu, Qiuqin, Haber, James E., Krogan, Nevan J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4167031/
https://ncbi.nlm.nih.gov/pubmed/25010907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2014.127
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