Systematic Triple Mutant Analysis Uncovers Functional Connectivity Between Pathways Involved in Chromosome Regulation

Genetic interactions reveal the functional relationships between pairs of genes. In this study, we describe a method for the systematic generation and quantitation of triple mutants, termed Triple Mutant Analysis (TMA). We have used this approach to interrogate partially redundant pairs of genes in...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Haber, James E., Braberg, Hannes, Wu, Qiuqin, Alexander, Richard, Haase, Julian, Ryan, Colm, Lipkin-Moore, Zach, Franks-Skiba, Kathleen E., Johnson, Tasha, Shales, Michael, Lenstra, Tineke L., Holstege, Frank C. P., Johnson, Jeffrey R., Bloom, Kerry, Krogan, Nevan J.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3718395/
https://ncbi.nlm.nih.gov/pubmed/23746449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.05.007
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires