A Genetic Interaction Map of RNA Processing Factors Reveals Links Between Sem1/Dss1-Containing Complexes and mRNA Export and Splicing

We used a quantitative, high-density genetic interaction map, or E-MAP (Epistatic MiniArray Profile), to interrogate the relationships within and between RNA processing pathways. Due to their complexity, and the essential roles of many of the components, these pathways have been difficult to functio...

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Autori principali: Wilmes, Gwendolyn M., Bergkessel, Megan, Bandyopadhyay, Sourav, Shales, Michael, Braberg, Hannes, Cagney, Gerard, Collins, Sean R., Whitworth, Gregg B., Kress, Tracy L., Weissman, Jonathan S., Ideker, Trey, Guthrie, Christine, Krogan, Nevan J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2644724/
https://ncbi.nlm.nih.gov/pubmed/19061648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2008.11.012
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