Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy

BACKGROUND: Functional disturbances of the endoplasmic reticulum (ER) lead to activation of the unfolded protein response (UPR), which is involved in the consecutive steps of carcinogenesis. In human hepatocellular carcinoma (HCC), the UPR is shown to be activated; however, little is known about the...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Hepatol Int
Main Authors: Vandewynckel, Yves-Paul, Laukens, Debby, Bogaerts, Eliene, Paridaens, Annelies, Van den Bussche, Anja, Verhelst, Xavier, Van Steenkiste, Christophe, Descamps, Benedicte, Vanhove, Chris, Libbrecht, Louis, De Rycke, Riet, Lambrecht, Bart N., Geerts, Anja, Janssens, Sophie, Van Vlierberghe, Hans
Format: Artigo
Sprog:Inglês
Udgivet: Springer India 2014
Fag:
Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289530/
https://ncbi.nlm.nih.gov/pubmed/25598862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12072-014-9582-0
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker