Thrombin drives tumorigenesis in colitis-associated colon cancer

The established association between inflammatory bowel disease and colorectal cancer underscores the importance of inflammation in colon cancer development. Based on evidence that hemostatic proteases are powerful modifiers of both inflammatory pathologies and tumor biology, gene-targeted mice carry...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Turpin, Brian, Miller, Whitney, Rosenfeldt, Leah, Kombrinck, Keith, Flick, Matthew J., Steinbrecher, Kris A., Harmel-Laws, Eleana, Mullins, Eric S., Shaw, Maureen, Witte, David P., Revenko, Alexey, Monia, Brett, Palumbo, Joseph S.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288815/
https://ncbi.nlm.nih.gov/pubmed/24710407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-3276
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