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Essential role for autophagy during invariant NKT cell development

Autophagy is an evolutionarily conserved cellular homeostatic pathway essential for development, immunity, and cell death. Although autophagy modulates MHC antigen presentation, it remains unclear whether autophagy defects impact on CD1d lipid loading and presentation to invariant natural killer T (...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Salio, Mariolina, Puleston, Daniel J., Mathan, Till S. M., Shepherd, Dawn, Stranks, Amanda J., Adamopoulou, Eleni, Veerapen, Natacha, Besra, Gurdyal S., Hollander, Georg A., Simon, Anna Katharina, Cerundolo, Vincenzo
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284579/
https://ncbi.nlm.nih.gov/pubmed/25512546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413935112
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