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Essential role for autophagy during invariant NKT cell development

Autophagy is an evolutionarily conserved cellular homeostatic pathway essential for development, immunity, and cell death. Although autophagy modulates MHC antigen presentation, it remains unclear whether autophagy defects impact on CD1d lipid loading and presentation to invariant natural killer T (...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Salio, Mariolina, Puleston, Daniel J., Mathan, Till S. M., Shepherd, Dawn, Stranks, Amanda J., Adamopoulou, Eleni, Veerapen, Natacha, Besra, Gurdyal S., Hollander, Georg A., Simon, Anna Katharina, Cerundolo, Vincenzo
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284579/
https://ncbi.nlm.nih.gov/pubmed/25512546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413935112
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