Essential role for autophagy during invariant NKT cell development

Autophagy is an evolutionarily conserved cellular homeostatic pathway essential for development, immunity, and cell death. Although autophagy modulates MHC antigen presentation, it remains unclear whether autophagy defects impact on CD1d lipid loading and presentation to invariant natural killer T (...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Salio, Mariolina, Puleston, Daniel J., Mathan, Till S. M., Shepherd, Dawn, Stranks, Amanda J., Adamopoulou, Eleni, Veerapen, Natacha, Besra, Gurdyal S., Hollander, Georg A., Simon, Anna Katharina, Cerundolo, Vincenzo
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2014
Materias:
PNAS Plus
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284579/
https://ncbi.nlm.nih.gov/pubmed/25512546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413935112
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