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Essential role for autophagy during invariant NKT cell development

Autophagy is an evolutionarily conserved cellular homeostatic pathway essential for development, immunity, and cell death. Although autophagy modulates MHC antigen presentation, it remains unclear whether autophagy defects impact on CD1d lipid loading and presentation to invariant natural killer T (...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Salio, Mariolina, Puleston, Daniel J., Mathan, Till S. M., Shepherd, Dawn, Stranks, Amanda J., Adamopoulou, Eleni, Veerapen, Natacha, Besra, Gurdyal S., Hollander, Georg A., Simon, Anna Katharina, Cerundolo, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284579/
https://ncbi.nlm.nih.gov/pubmed/25512546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413935112
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