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Essential role for autophagy during invariant NKT cell development

Autophagy is an evolutionarily conserved cellular homeostatic pathway essential for development, immunity, and cell death. Although autophagy modulates MHC antigen presentation, it remains unclear whether autophagy defects impact on CD1d lipid loading and presentation to invariant natural killer T (...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Salio, Mariolina, Puleston, Daniel J., Mathan, Till S. M., Shepherd, Dawn, Stranks, Amanda J., Adamopoulou, Eleni, Veerapen, Natacha, Besra, Gurdyal S., Hollander, Georg A., Simon, Anna Katharina, Cerundolo, Vincenzo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2014
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284579/
https://ncbi.nlm.nih.gov/pubmed/25512546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1413935112
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