The actin cytoskeleton modulates the activation of iNKT cells by segregating CD1d nanoclusters on antigen-presenting cells

Invariant natural killer T (iNKT) cells recognize endogenous and exogenous lipid antigens presented in the context of CD1d molecules. The ability of iNKT cells to recognize endogenous antigens represents a distinct immune recognition strategy, which underscores the constitutive memory phenotype of i...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Torreno-Pina, Juan A., Manzo, Carlo, Salio, Mariolina, Aichinger, Michael C., Oddone, Anna, Lakadamyali, Melike, Shepherd, Dawn, Besra, Gurdyal S., Cerundolo, Vincenzo, Garcia-Parajo, Maria F.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2016
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760795/
https://ncbi.nlm.nih.gov/pubmed/26798067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514530113
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