Amide Analogues of CD1d Agonists Modulate iNKT-Cell-Mediated Cytokine Production

[Image: see text] Invariant natural killer T (iNKT) cells are restricted by the non-polymorphic MHC class I-like protein, CD1d, and activated following presentation of lipid antigens bound to CD1d molecules. The prototypical iNKT cell agonist is α-galactosyl ceramide (α-GalCer). CD1d-mediated activa...

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Bibliographic Details
Main Authors: Wojno, Justyna, Jukes, John-Paul, Ghadbane, Hemza, Shepherd, Dawn, Besra, Gurdyal S., Cerundolo, Vincenzo, Cox, Liam R.
Format: Artigo
Language:Inglês
Published: American Chemical Society 2012
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3409616/
https://ncbi.nlm.nih.gov/pubmed/22324848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2005017
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