Active and inactive β1 integrins segregate into distinct nanoclusters in focal adhesions

Integrins are the core constituents of cell–matrix adhesion complexes such as focal adhesions (FAs) and play key roles in physiology and disease. Integrins fluctuate between active and inactive conformations, yet whether the activity state influences the spatial organization of integrins within FAs...

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Vydáno v:J Cell Biol
Hlavní autoři: Spiess, Matthias, Hernandez-Varas, Pablo, Oddone, Anna, Olofsson, Helene, Blom, Hans, Waithe, Dominic, Lock, John G., Lakadamyali, Melike, Strömblad, Staffan
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5987715/
https://ncbi.nlm.nih.gov/pubmed/29632027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201707075
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