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A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime

Cell-matrix adhesions are central mediators of mechanotransduction, yet the interplay between force and adhesion regulation remains unclear. Here we use live cell imaging to map time-dependent cross-correlations between vinculin-mediated tension and adhesion complex area, revealing a plastic, contex...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Hernández-Varas, Pablo, Berge, Ulrich, Lock, John G., Strömblad, Staffan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Pub. Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491829/
https://ncbi.nlm.nih.gov/pubmed/26109125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8524
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