Pre-complexation of talin and vinculin without tension is required for efficient nascent adhesion maturation

Talin and vinculin are mechanosensitive proteins that are recruited early to integrin-based nascent adhesions (NAs). In two epithelial cell systems with well-delineated NA formation, we find these molecules concurrently recruited to the subclass of NAs maturing to focal adhesions. After the initial...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:eLife
Päätekijät: Han, Sangyoon J, Azarova, Evgenia V, Whitewood, Austin J, Bachir, Alexia, Guttierrez, Edgar, Groisman, Alex, Horwitz, Alan R, Goult, Benjamin T, Dean, Kevin M, Danuser, Gaudenz
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: eLife Sciences Publications, Ltd 2021
Aiheet:
Cell Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009661/
https://ncbi.nlm.nih.gov/pubmed/33783351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66151
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia