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Pre-complexation of talin and vinculin without tension is required for efficient nascent adhesion maturation
Talin and vinculin are mechanosensitive proteins that are recruited early to integrin-based nascent adhesions (NAs). In two epithelial cell systems with well-delineated NA formation, we find these molecules concurrently recruited to the subclass of NAs maturing to focal adhesions. After the initial...
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| Udgivet i: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8009661/ https://ncbi.nlm.nih.gov/pubmed/33783351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.66151 |
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