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Focal adhesions are sites of integrin extension
Integrins undergo global conformational changes that specify their activation state. Current models portray the inactive receptor in a bent conformation that upon activation converts to a fully extended form in which the integrin subunit leg regions are separated to enable ligand binding and subsequ...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2845069/ https://ncbi.nlm.nih.gov/pubmed/20231384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200907174 |
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