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The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites

PINCH-1 is a LIM-only domain protein that forms a ternary complex with integrin-linked kinase (ILK) and parvin (to form the IPP complex) downstream of integrins. Here, we demonstrate that PINCH-1 (also known as Lims1) gene ablation in the epidermis of mice caused epidermal detachment from the baseme...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Karaköse, Esra, Geiger, Tamar, Flynn, Kevin, Lorenz-Baath, Katrin, Zent, Roy, Mann, Matthias, Fässler, Reinhard
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4342583/
https://ncbi.nlm.nih.gov/pubmed/25609703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.162545
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