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The Cytoplasmic Tyrosines of Integrin Subunit β1 Are Involved in Focal Adhesion Kinase Activation

We have previously shown that mutation of the two tyrosines in the cytoplasmic domain of integrin subunit β1 (Y783 and Y795) to phenylalanines markedly reduces the capability of β1A integrins to mediate directed cell migration. In this study, β1-dependent cell spreading was found to be delayed in GD...

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Detalhes bibliográficos
Main Authors: Wennerberg, Krister, Armulik, Annika, Sakai, Takao, Karlsson, Marjam, Fässler, Reinhard, Schaefer, Erik M., Mosher, Deane F., Johansson, Staffan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86053/
https://ncbi.nlm.nih.gov/pubmed/10891511
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