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β1 integrin cytoplasmic tyrosines promote skin tumorigenesis independent of their phosphorylation
β1 integrin tyrosine phosphorylation by oncogenic kinases, such as Src, has been predicted to induce tumorigenesis by disrupting adhesion and modifying integrin signaling. We directly tested this hypothesis by subjecting mice with “nonphosphorylatable” tyrosine-to-phenylalanine substitutions in the...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174600/ https://ncbi.nlm.nih.gov/pubmed/21876123 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105689108 |
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