In vivo β1 integrin function requires phosphorylation-independent regulation by cytoplasmic tyrosines

Integrins are heterodimeric adhesion receptors associated with bidirectional signaling. In vitro studies support a role for the binding of evolutionarily conserved tyrosine motifs (NPxY) in the β integrin cytoplasmic tail to phosphotyrosine-binding (PTB) domain-containing proteins, an interaction pr...

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Detalhes bibliográficos
Main Authors: Chen, Hong, Zou, Zhiying, Sarratt, Kendra L., Zhou, Diane, Zhang, MaoZhen, Sebzda, Eric, Hammer, Daniel A., Kahn, Mark L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2006
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472300/
https://ncbi.nlm.nih.gov/pubmed/16618804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1408306
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