Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo

Src homology 2 domain–containing leukocyte phosphoprotein of 76 kD (SLP76), an adaptor that plays a critical role in platelet activation in vitro, contains three N-terminal tyrosine residues that are essential for its function. We demonstrate that mice containing complementary tyrosine to phenylalan...

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Bibliografiske detaljer
Main Authors: Bezman, Natalie A., Lian, Lurong, Abrams, Charles S., Brass, Lawrence F., Kahn, Mark L., Jordan, Martha S., Koretzky, Gary A.
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2008
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525600/
https://ncbi.nlm.nih.gov/pubmed/18663126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20080240
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