The Cytoplasmic Tyrosines of Integrin Subunit β1 Are Involved in Focal Adhesion Kinase Activation

We have previously shown that mutation of the two tyrosines in the cytoplasmic domain of integrin subunit β1 (Y783 and Y795) to phenylalanines markedly reduces the capability of β1A integrins to mediate directed cell migration. In this study, β1-dependent cell spreading was found to be delayed in GD...

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Main Authors: Wennerberg, Krister, Armulik, Annika, Sakai, Takao, Karlsson, Marjam, Fässler, Reinhard, Schaefer, Erik M., Mosher, Deane F., Johansson, Staffan
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2000
Teme:
Cell Growth and Development
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC86053/
https://ncbi.nlm.nih.gov/pubmed/10891511
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