The Cytoplasmic Tyrosines of Integrin Subunit β1 Are Involved in Focal Adhesion Kinase Activation

We have previously shown that mutation of the two tyrosines in the cytoplasmic domain of integrin subunit β1 (Y783 and Y795) to phenylalanines markedly reduces the capability of β1A integrins to mediate directed cell migration. In this study, β1-dependent cell spreading was found to be delayed in GD...

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Autors principals: Wennerberg, Krister, Armulik, Annika, Sakai, Takao, Karlsson, Marjam, Fässler, Reinhard, Schaefer, Erik M., Mosher, Deane F., Johansson, Staffan
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2000
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86053/
https://ncbi.nlm.nih.gov/pubmed/10891511
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