Invariant NKT cells reduce the immunosuppressive activity of influenza A virus–induced myeloid-derived suppressor cells in mice and humans

Infection with influenza A virus (IAV) presents a substantial threat to public health worldwide, with young, elderly, and immunodeficient individuals being particularly susceptible. Inflammatory responses play an important role in the fatal outcome of IAV infection, but the mechanism remains unclear...

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Detalhes bibliográficos
Main Authors: De Santo, Carmela, Salio, Mariolina, Masri, S. Hajar, Lee, Laurel Yong-Hwa, Dong, Tao, Speak, Anneliese O., Porubsky, Stefan, Booth, Sarah, Veerapen, Natacha, Besra, Gurdyal S., Gröne, Hermann-Josef, Platt, Frances M., Zambon, Maria, Cerundolo, Vincenzo
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2008
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2582442/
https://ncbi.nlm.nih.gov/pubmed/19033672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36264
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