Saposins modulate human invariant Natural Killer T cells self-reactivity and facilitate lipid exchange with CD1d molecules during antigen presentation

Lipid transfer proteins, such as molecules of the saposin family, facilitate extraction of lipids from biological membranes for their loading onto CD1d molecules. Although it has been shown that prosaposin-deficient mice fail to positively select invariant natural killer T (iNKT) cells, it remains u...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Salio, Mariolina, Ghadbane, Hemza, Dushek, Omer, Shepherd, Dawn, Cypen, Jeremy, Gileadi, Uzi, Aichinger, Michael C., Napolitani, Giorgio, Qi, Xiaoyang, van der Merwe, P. Anton, Wojno, Justyna, Veerapen, Natacha, Cox, Liam R., Besra, Gurdyal S., Yuan, Weiming, Cresswell, Peter, Cerundolo, Vincenzo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
PNAS Plus
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3856826/
https://ncbi.nlm.nih.gov/pubmed/24248359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1310050110
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