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Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules
CD1d molecules bind lipid antigens in the endocytic pathway, and access to the pathway is important for the development of CD1d-restricted natural killer T (NKT) cells. Saposins, derived from a common precursor, prosaposin, are small, heat-stable lysosomal glycoproteins required for lysosomal degrad...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1838443/ https://ncbi.nlm.nih.gov/pubmed/17372201 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700617104 |
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