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Saposin B is the dominant saposin that facilitates lipid binding to human CD1d molecules

CD1d molecules bind lipid antigens in the endocytic pathway, and access to the pathway is important for the development of CD1d-restricted natural killer T (NKT) cells. Saposins, derived from a common precursor, prosaposin, are small, heat-stable lysosomal glycoproteins required for lysosomal degrad...

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Detaylı Bibliyografya
Asıl Yazarlar: Yuan, Weiming, Qi, Xiaoyang, Tsang, Pansy, Kang, Suk-Jo, Illarionov, Petr A., Besra, Gurdyal S., Gumperz, Jenny, Cresswell, Peter
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2007
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1838443/
https://ncbi.nlm.nih.gov/pubmed/17372201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0700617104
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