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Saposins utilize two strategies for lipid transfer and CD1 antigen presentation
Transferring lipid antigens from membranes into CD1 antigen-presenting proteins represents a major molecular hurdle necessary for T-cell recognition. Saposins facilitate this process, but the mechanisms used are not well understood. We found that saposin B forms soluble saposin protein–lipid complex...
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| Main Authors: | , , , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3311357/ https://ncbi.nlm.nih.gov/pubmed/22331868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1200764109 |
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