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Hedgehog-induced phosphorylation by CK1 sustains the activity of Ci/Gli activator

Hedgehog (Hh) signaling governs many developmental processes by regulating the balance between the repressor (Ci(R)/Gli(R)) and activator (Ci(A)/Gli(A)) forms of Cubitus interruptus (Ci)/glioma-associated oncogene homolog (Gli) transcription factors. Although much is known about how Ci(R)/Gli(R) is...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Shi, Qing, Li, Shuang, Li, Shuangxi, Jiang, Alice, Chen, Yongbin, Jiang, Jin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4284548/
https://ncbi.nlm.nih.gov/pubmed/25512501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416652111
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