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Suppressor of fused impedes Ci/Gli nuclear import by opposing Trn/Kapβ2 in Hedgehog signaling

The Hedgehog (Hh) family of secreted proteins governs many key developmental processes by regulating Ci/Gli transcription factors at multiple levels including nuclear–cytoplasmic shuttling. Here, we investigate the mechanism underlying the regulation of Ci/Gli subcellular localization by identifying...

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Detalhes bibliográficos
Main Authors: Shi, Qing, Han, Yuhong, Jiang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3937776/
https://ncbi.nlm.nih.gov/pubmed/24413177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.142828
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