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Structural insight into the mutual recognition and regulation between Suppressor of Fused and Gli/Ci
Hedgehog (Hh) signaling regulates embryonic development and adult tissue homeostasis. Mutations of its pathway components including Suppressor of Fused (Sufu) and Gli/Ci predispose to cancers and congenital anomalies. The Sufu-Gli protein complex occupies a central position in the vertebrate Hh sign...
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| Publicado no: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5842692/ https://ncbi.nlm.nih.gov/pubmed/24217340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms3608 |
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