Phosphorylation of Ci/Gli by Fused family kinases promotes Hedgehog signaling

Hedgehog (Hh) signaling culminates in the conversion of the latent transcription factor Cubitus interruptus (Ci)/Gli into its activator form (Ci(A)/Gli(A)), but the underlying mechanism remains poorly understood. Here we demonstrate that Hh stimulates the phosphorylation of Ci by the Ser/Thr kinase...

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Detaylı Bibliyografya
Yayımlandı:Dev Cell
Asıl Yazarlar: Han, Yuhong, Wang, Bing, Cho, Yong Suk, Zhu, Jian, Wu, Jiang, Chen, Yongbin, Jiang, Jin
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2019
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736714/
https://ncbi.nlm.nih.gov/pubmed/31279575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2019.06.008
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