Caricamento...
Small Molecule p75(NTR) Ligands Reduce Pathological Phosphorylation and Misfolding of Tau, Inflammatory Changes, Cholinergic Degeneration, and Cognitive Deficits in AβPP(L/S) Transgenic Mice
The p75 neurotrophin receptor (p75(NTR) ) is involved in degenerative mechanisms related to Alzheimer’s disease (AD). In addition, p75(NTR) levels are increased in AD and the receptor is expressed by neurons that are particularly vulnerable in the disease. Therefore, modulating p75(NTR) function may...
Salvato in:
| Pubblicato in: | J Alzheimers Dis |
|---|---|
| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4278429/ https://ncbi.nlm.nih.gov/pubmed/24898660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-140036 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|