Small Molecule p75(NTR) Ligands Reduce Pathological Phosphorylation and Misfolding of Tau, Inflammatory Changes, Cholinergic Degeneration, and Cognitive Deficits in AβPP(L/S) Transgenic Mice

Lignende værker

• The p75 Neurotrophin Receptor Promotes Amyloid-β(1-42)-Induced Neuritic Dystrophy In Vitro and In Vivo
  af: Knowles, Juliet K., et al.
  Udgivet: (2009)
• Thy1-hAPP(Lond/Swe+) mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function
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  Udgivet: (2012)
• A small molecule p75(NTR) ligand normalizes signalling and reduces Huntington’s disease phenotypes in R6/2 and BACHD mice
  af: Simmons, Danielle A., et al.
  Udgivet: (2016)
• A Small Molecule p75(NTR) Ligand, LM11A-31, Reverses Cholinergic Neurite Dystrophy in Alzheimer's Disease Mouse Models with Mid- to Late-Stage Disease Progression
  af: Simmons, Danielle A., et al.
  Udgivet: (2014)
• The Role of p75(NTR) in Cholinergic Basal Forebrain Structure and Function
  af: Boskovic, Zoran, et al.
  Udgivet: (2014)