Thy1-hAPP(Lond/Swe+) mouse model of Alzheimer's disease displays broad behavioral deficits in sensorimotor, cognitive and social function

Alzheimer's disease (AD), the most common form of dementia, is an age-dependent progressive neurodegenerative disorder. β-amyloid, a metabolic product of the amyloid precursor protein (APP), plays an important role in the pathogenesis of AD. The Thy1-hAPP(Lond/Swe+) (line 41) transgenic mouse o...

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Detalhes bibliográficos
Main Authors: Faizi, Mehrdad, Bader, Patrick L, Saw, Nay, Nguyen, Thuy-Vi V, Beraki, Simret, Wyss-Coray, Tony, Longo, Frank M, Shamloo, Mehrdad
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Inc 2012
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3345358/
https://ncbi.nlm.nih.gov/pubmed/22574282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.41
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