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ARAP3 Functions in Hematopoietic Stem Cells
ARAP3 is a GTPase-activating protein (GAP) that inactivates Arf6 and RhoA small GTPases. ARAP3 deficiency in mice causes a sprouting angiogenic defect resulting in embryonic lethality by E11. Mice with an ARAP3 R302,303A mutation (Arap3(KI/KI)) that prevents activation by phosphoinositide-3-kinase (...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4277471/ https://ncbi.nlm.nih.gov/pubmed/25542002 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116107 |
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