Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3

Hematopoietic stem cells (HSC) are primarily dormant but have the potential to become highly active on demand to reconstitute blood. This requires a swift metabolic switch from glycolysis to mitochondrial oxidative phosphorylation. Maintenance of low levels of reactive oxygen species (ROS), a by-pro...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:EMBO Rep
Autori principali: Rimmelé, Pauline, Liang, Raymond, Bigarella, Carolina L, Kocabas, Fatih, Xie, Jingjing, Serasinghe, Madhavika N, Chipuk, Jerry, Sadek, Hesham, Zhang, Cheng Cheng, Ghaffari, Saghi
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Ltd 2015
Soggetti:
Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576984/
https://ncbi.nlm.nih.gov/pubmed/26209246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439704
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi