Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3

Hematopoietic stem cells (HSC) are primarily dormant but have the potential to become highly active on demand to reconstitute blood. This requires a swift metabolic switch from glycolysis to mitochondrial oxidative phosphorylation. Maintenance of low levels of reactive oxygen species (ROS), a by-pro...

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Bibliografski detalji
Izdano u:EMBO Rep
Glavni autori: Rimmelé, Pauline, Liang, Raymond, Bigarella, Carolina L, Kocabas, Fatih, Xie, Jingjing, Serasinghe, Madhavika N, Chipuk, Jerry, Sadek, Hesham, Zhang, Cheng Cheng, Ghaffari, Saghi
Format: Artigo
Jezik:Inglês
Izdano: John Wiley & Sons, Ltd 2015
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576984/
https://ncbi.nlm.nih.gov/pubmed/26209246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439704
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