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Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3
Hematopoietic stem cells (HSC) are primarily dormant but have the potential to become highly active on demand to reconstitute blood. This requires a swift metabolic switch from glycolysis to mitochondrial oxidative phosphorylation. Maintenance of low levels of reactive oxygen species (ROS), a by-pro...
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| Gepubliceerd in: | EMBO Rep |
|---|---|
| Hoofdauteurs: | , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
John Wiley & Sons, Ltd
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4576984/ https://ncbi.nlm.nih.gov/pubmed/26209246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439704 |
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