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Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3
Hematopoietic stem cells (HSC) are primarily dormant but have the potential to become highly active on demand to reconstitute blood. This requires a swift metabolic switch from glycolysis to mitochondrial oxidative phosphorylation. Maintenance of low levels of reactive oxygen species (ROS), a by-pro...
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| 出版年: | EMBO Rep |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley & Sons, Ltd
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4576984/ https://ncbi.nlm.nih.gov/pubmed/26209246 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439704 |
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