Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3

Hematopoietic stem cells (HSC) are primarily dormant but have the potential to become highly active on demand to reconstitute blood. This requires a swift metabolic switch from glycolysis to mitochondrial oxidative phosphorylation. Maintenance of low levels of reactive oxygen species (ROS), a by-pro...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO Rep
Egile Nagusiak: Rimmelé, Pauline, Liang, Raymond, Bigarella, Carolina L, Kocabas, Fatih, Xie, Jingjing, Serasinghe, Madhavika N, Chipuk, Jerry, Sadek, Hesham, Zhang, Cheng Cheng, Ghaffari, Saghi
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley & Sons, Ltd 2015
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576984/
https://ncbi.nlm.nih.gov/pubmed/26209246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439704
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