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Evidence for AKT-independent regulation of FOXO1 and FOXO3 in haematopoietic stem and progenitor cells

Transcription factors FOXOs (1, 3, 4) are essential for the maintenance of haematopoietic stem cells. FOXOs are evolutionary conserved substrates of the AKT serine threonine protein kinase that are also phosphorylated by several kinases other than AKT. Specifically, phosphorylation by AKT is known t...

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Publicat a:Cell Cycle
Autors principals: Liang, Raymond, Rimmelé, Pauline, Bigarella, Carolina L., Yalcin, Safak, Ghaffari, Saghi
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845935/
https://ncbi.nlm.nih.gov/pubmed/26929388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1123355
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