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Evidence for AKT-independent regulation of FOXO1 and FOXO3 in haematopoietic stem and progenitor cells

Transcription factors FOXOs (1, 3, 4) are essential for the maintenance of haematopoietic stem cells. FOXOs are evolutionary conserved substrates of the AKT serine threonine protein kinase that are also phosphorylated by several kinases other than AKT. Specifically, phosphorylation by AKT is known t...

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Pubblicato in:Cell Cycle
Autori principali: Liang, Raymond, Rimmelé, Pauline, Bigarella, Carolina L., Yalcin, Safak, Ghaffari, Saghi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4845935/
https://ncbi.nlm.nih.gov/pubmed/26929388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2015.1123355
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