Dnmt3a and Dnmt3b have Overlapping and Distinct Functions in Hematopoietic Stem Cells

Hematopoietic stem cells (HSCs) are the precursors of the hematopoietic system responsible for the lifelong production of blood and bone marrow. Given the emerging importance of epigenetic regulation in HSC fate decisions and malignant transformation, we investigated the role of the DNA methyltransf...

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Autori principali: Challen, Grant A., Sun, Deqiang, Mayle, Allison, Jeong, Mira, Luo, Min, Rodriguez, Benjamin, Mallaney, Cates, Celik, Hamza, Yang, Liubin, Xia, Zheng, Cullen, Sean, Berg, Jonathan, Zheng, Yayun, Darlington, Gretchen J., Li, Wei, Goodell, Margaret A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4163922/
https://ncbi.nlm.nih.gov/pubmed/25130491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2014.06.018
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