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Analysis of mRNA recognition by human thymidylate synthase
Expression of hTS (human thymidylate synthase), a key enzyme in thymidine biosynthesis, is regulated on the translational level through a feedback mechanism that is rarely found in eukaryotes. At low substrate concentrations, the ligand-free enzyme binds to its own mRNA and stabilizes a hairpin stru...
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| Publicat a: | Biosci Rep |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Portland Press Ltd.
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4274661/ https://ncbi.nlm.nih.gov/pubmed/25423174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140137 |
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