Analysis of mRNA recognition by human thymidylate synthase

Expression of hTS (human thymidylate synthase), a key enzyme in thymidine biosynthesis, is regulated on the translational level through a feedback mechanism that is rarely found in eukaryotes. At low substrate concentrations, the ligand-free enzyme binds to its own mRNA and stabilizes a hairpin stru...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biosci Rep
Main Authors: Brunn, Nicholas D., Dibrov, Sergey M., Kao, Melody B., Ghassemian, Majid, Hermann, Thomas
Format: Artigo
Jezik:Inglês
Izdano: Portland Press Ltd. 2014
Teme:
Original Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274661/
https://ncbi.nlm.nih.gov/pubmed/25423174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20140137
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