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Translational repression of thymidylate synthase by targeting its mRNA
Resistance to drugs targeting human thymidylate synthase (TS) poses a major challenge in the field of anti-cancer therapeutics. Overexpression of the TS protein has been implicated as one of the factors leading to the development of resistance. Therefore, repressing translation by targeting the TS m...
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| Główni autorzy: | , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2013
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3627590/ https://ncbi.nlm.nih.gov/pubmed/23423353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt098 |
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