Translational repression of thymidylate synthase by targeting its mRNA

Resistance to drugs targeting human thymidylate synthase (TS) poses a major challenge in the field of anti-cancer therapeutics. Overexpression of the TS protein has been implicated as one of the factors leading to the development of resistance. Therefore, repressing translation by targeting the TS m...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Garg, Divita, Beribisky, Alexander V., Ponterini, Glauco, Ligabue, Alessio, Marverti, Gaetano, Martello, Andrea, Costi, M. Paola, Sattler, Michael, Wade, Rebecca C.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Oxford University Press 2013
Aiheet:
Molecular Biology
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627590/
https://ncbi.nlm.nih.gov/pubmed/23423353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt098
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