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Translational repression of thymidylate synthase by targeting its mRNA

Resistance to drugs targeting human thymidylate synthase (TS) poses a major challenge in the field of anti-cancer therapeutics. Overexpression of the TS protein has been implicated as one of the factors leading to the development of resistance. Therefore, repressing translation by targeting the TS m...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Garg, Divita, Beribisky, Alexander V., Ponterini, Glauco, Ligabue, Alessio, Marverti, Gaetano, Martello, Andrea, Costi, M. Paola, Sattler, Michael, Wade, Rebecca C.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2013
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3627590/
https://ncbi.nlm.nih.gov/pubmed/23423353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt098
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